Mesotherapy: Unlocking the secret weapon of deep youthfulness of the skin

1. Introduction: The "powerlessness" of traditional skin care and the rise of mesotherapy

In the pursuit of beauty, we put a lot of effort into selecting the most expensive serums, expecting them to work wonders. However, have you ever wondered how much of these expensive ingredients can actually penetrate the "battlefield" where they work?

The stratum corneum of human skin is a powerful natural barrier. Although it protects us from external aggressors, it also hinders the absorption of active ingredients. According to scientific statistics, the absorption rate of traditional smear-type skin care products is often less than 10%. This means that most of your investment stays on the surface of your skin, unable to reach the dermis that truly determines whether your skin looks young or not.

It is in this context that a precise and efficient medical aesthetic technology that reaches the bottom of the skin has emerged, which is Mesotherapy, which has become popular all over the world in recent years. This somewhat academic name actually contains the revolutionary skin care concept of "delivering nutrients directly to the dermis". It no longer stops at the surface but penetrates deep into the core of the skin, providing you with a secret weapon to unlock youthfulness for those who desire deep, lasting improvement in skin texture.

This article will lead you to gain an in-depth understanding of the scientific principles of mesotherapy, diverse application scenarios, mainstream operation methods, and how to safely and effectively use this technology to achieve your desire for healthy and beautiful skin.

2. Scientific Origin: The mechanism of mesotherapy is correct

To understand the effectiveness of mesotherapy, we must first identify the target of its action - the mesoderm.

What is the "mesoderm"? The dermis is the key!

In skin anatomy, the "mesoderm" refers specifically to the dermis layer that lies beneath the epidermis layer, and the deeper layer of subcutaneous fat.

The dermis is the skin's "core support structure" and is rich in:

• Collagen and elastin fibers: Determines the elasticity and firmness of the skin.

• Hyaluronic acid (hyaluronic acid): A powerful natural moisturizing factor responsible for the skin's hydration and plumpness.

• Blood vessels, nerves, and accessory structures: Responsible for nutrient transport and metabolism.

Therefore, to truly improve the skin's fine lines, sagging, dryness, and dullness, nutrients must be delivered directly to and act on this critical dermis layer.

Precise Delivery: Breaks through the skin barrier

The history of mesotherapy dates back to France in 1952 and was first proposed by Dr. Michel Pistor. At its core, it uses minimally invasive (such as microneedling or water light injection) or non-invasive techniques (such as electroporation) to create tens of thousands of tiny channels on the skin, allowing for "transdermal absorption" of active ingredients.

This direct and efficient delivery method increases the absorption efficiency exponentially compared to smear-based skincare, ensuring that nutrients are fully absorbed and utilized in the dermis.

"Cocktail" Customized Therapy: Personalized Configuration

Mesotherapy is not a single-ingredient injection, but a highly customized "cocktail recipe". This is the key to its strong customization and targeting.

Doctors usually use **non-cross-linked hyaluronic acid (small molecule)** as the basic carrier, combined with various highly active functional ingredients:

Through precise blending, mesotherapy can achieve "one person, one body, one policy", truly meeting the personalized needs of different skin types and problems.

3. Wide application and core benefits of mesotherapy

Mesotherapy is widely used in the field of medical aesthetics due to its precise level of action and diversity of formulations, and can improve almost all mainstream skin problems.

Anti-aging and regeneration of the skin

• Deep Hydration and Elasticity Enhancement: Ingredients such as hyaluronic acid are injected directly into the dermis to quickly replenish moisture, improve the skin's dryness and roughness, and fundamentally restore skin hydration, elasticity, and radiance.

• Stimulating collagen regeneration: The minimally invasive process itself is also a kind of "micro-damage", which can stimulate the skin's own repair mechanism and promote the regeneration of collagen and elastin fibers, thereby achieving the effect of tightening the skin and improving fine lines.

Skin texture improvement and radiance enhancement

Mesotherapy significantly improves the skin's microenvironment:

• Brightens and evens out skin tone, lightens facial dullness.

• Repairs photodamage and assists in the improvement of superficial pigmentation.

• Balances oil secretion, shrinks pores for more refined skin.

Assists in treating problem skin

For some stubborn problem skin, mesotherapy can also be used as an aid:

• Acne scars and dimples: Combined with growth factors and hyaluronic acid to promote tissue repair and filling.

• Rosacea and Sensitive Skin: Targeted delivery of repairing and anti-inflammatory ingredients to help stabilize and strengthen the skin barrier.

Expand applications: hair nourishment and shaping

The idea of mesotherapy applies to other parts of the body as well:

• Hair growth and nourishment: Deliver hair growth factors, vitamins, trace elements, etc. to the depths of the scalp hair follicles through microneedling or injection to improve hair follicle microcirculation, activate hair follicles, and assist in the treatment of hair loss problems (such as androgenetic alopecia).

• Local Shaping: (Requires professional evaluation and guidance) Use lipolytic ingredients to inject into the subcutaneous fat layer to reduce local fat accumulation.

4. Understand the operation method: from water light needle to needle-free penetration

With the advancement of technology, the delivery methods of mesotherapy are becoming more and more diverse to meet the pursuit of comfort and effectiveness among different populations.

Injection: accurate and direct

This is the most mainstream method in medical aesthetic institutions, relying on professional injection equipment:

• Water light injector (negative pressure multi-needle): such as Vital Injector or Hycoox, etc. Using negative pressure to adsorb the skin, multiple extremely thin needles (usually 5 or 9 needles) evenly inject the agent into the dermis at a constant and precise depth and dose, greatly improving the uniformity and efficiency of treatment and reducing pain.

• Freehand injection: highly dependent on the experience and skill of doctors, suitable for focused enhancements or minor adjustments to specific areas.

Non-injectable: minimally invasive and non-invasive

For people who are afraid of needles or have extremely sensitive skin:

• Electric microneedling/rollers: Tens of thousands of vertical microchannels are created on the skin surface through high-speed vibrating microneedles, and then nutrient solutions are applied to the skin, using channels to penetrate into the dermis.

• Electroporation Technology (Needle-Free Water Light): Uses specific pulsed radio waves to create instantaneously reversible micropores on the cell membrane, introducing hydrophilic molecules into the deep layers of the skin for needle-free penetration.

• Pneumatic injection (pneumatic water light): uses high-pressure gas to "push" nutrients into the skin, with the characteristics of needle-free, heat-free, and painless.

Treatment course planning: multiple treatments, superimposed effects

Mesotherapy is not a "set and forget" process, skin metabolism and aging are an ongoing process. General recommendations:

• Initial treatment: Usually required $3 \sim 5$ Times, each interval $2 \sim 4$ week, so that the skin condition is optimal.

• Maintenance: After completing the treatment, it is recommended to per $2 \sim 3$ Performed once a month to maintain the health and vitality of the dermis.

5. Risk prevention and efficient postoperative care

Mesotherapy is a safe and efficient aesthetic program, but its effectiveness and safety are highly dependent on professional operation and postoperative care.

Golden care period after surgery: moisturizing and sun protection

The skin after surgery is in the "minimally invasive" repair period and is sensitive to external stimuli, and care is crucial at this time:

• Strict moisturizing: postoperatively $72$ Within hours is the golden period for hydration, and it is necessary to use a lot of medical repair masks and gentle moisturizing products to provide an adequate water environment for skin repair.

• Hardcore sun protection: Absolutely avoid direct sunlight. When going out, you must use a high-multiplier sunscreen, combined with physical sunscreen (hat, mask), to prevent pigmentation.

• Avoid irritation: Avoid skin care products containing alcohol, acids (AHAs, salicylic acid, etc.), whitening, exfoliating, scrubs, and other irritating ingredients for a week.

• Avoid high temperatures: Avoid going to hot and sweaty places for a week, such as saunas, hot springs, strenuous exercise, etc., to avoid affecting the healing of minimally wounds.

Risk warning and selection suggestions

There are certain risks associated with any aesthetic program, and the main risks of mesotherapy include:

• Minor reactions: Slight redness, swelling, small blood spots, or bruising may occur after surgery, usually in the $3 \sim 7$ It subsides on its own within a day.

• Risk of infection: Unclean operating environment or improper postoperative care can lead to infection.

• Selection advice: Be sure to choose a formal medical aesthetic institution and experienced professional doctors for operation. Ensure that the injectable products used are legal and compliant medical devices or drugs.

6. Summary and outlook

Mesotherapy has revolutionized our definition of "high-performance skincare" with its unique advantage of reaching directly to the dermis and customized formulations. It's not just a simple hydration, it's a deep, systematic skin health management solution.

With the continuous development of biotechnology and medical aesthetic devices, the formulation of mesotherapy will become more and more refined, and the delivery technology will become more and more comfortable and non-invasive.

If you're tired of futile superficial effort and crave a youthful glow that's long-lasting and healthy from the inside out, mesotherapy is undoubtedly a highly effective choice worth diving deeper into and trying. Consult your dermatologist or aesthetic professional to develop your own Mesodermal skin rejuvenation plan!