R&D & Manufacturing Experts | Aowita: Global Supplier of Crosslinked HA Gels

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer & Global Supplier for Aesthetic and Medical Use
Cross-linked Hyaluronic Acid Sodium Gel Manufacturer & Global Supplier for Aesthetic and Medical Use

Cross-linked HA Gel R&D · Manufacturing · Global Supply Medical Aesthetic Filler Solutions

Type

Hand Dorsum

Type

Hand Dorsum

Type

Hand Dorsum

Application

The back of the hands, face, eye area, lips, and neck—improve skin texture and fine lines.

Application

The back of the hands, face, eye area, lips, and neck—improve skin texture and fine lines.

Application

The back of the hands, face, eye area, lips, and neck—improve skin texture and fine lines.

Place of Origin

China

Place of Origin

China

Place of Origin

China

Brand Name

Rveiling

Brand Name

Rveiling

Brand Name

Rveiling

Aowita Cross-linked HA Gel—Globally Available, Pursuing Exceptional Aesthetic Results

Aowita Cross-linked HA Gel—Globally Available, Pursuing Exceptional Aesthetic Results

Aowita Cross-linked HA Gel—Globally Available, Pursuing Exceptional Aesthetic Results

Product Ingredients:

Sodium Hyaluronate 20mg/mL, Lidocaine Hydrochloride 3mg/mL, Sodium Chloride, Injection Water, Phosphate Buffer System.

Product Characteristics

Rveiling® Vital features a micro-crosslinked micro-particle structure containing approximately 400,000 micro-gel particles per milliliter, supplemented with a small amount of free sodium hyaluronate gel. The primary ingredient, sodium hyaluronate, is prepared via microbial fermentation and packaged in a single-use, pre-filled syringe. The addition of lidocaine hydrochloride reduces patient discomfort during treatment.

Mechanism of Action

Rveiling® Vital's micro-particle micro-crosslinked structure and fine texture make it suitable for superficial dermal injections. By filling dermal tissue through injection, it modifies and improves skin texture and fine lines to achieve satisfactory results.


Indications

Rveiling® Vital is indicated for use in individuals aged 18 years and older for the back of the hands, face, periorbital area, lips, and neck. Its micro-crosslinked, fine-particle structure and smooth texture make it suitable for superficial dermal injection to enhance skin volume and appearance.

Sterilization Method

The gel within the pre-filled syringe undergoes steam sterilization at high temperature. This product is for single-use only.

Shelf Life: 36 months


Core Technology

Utilizes a novel patented cross-linking technology combining natural entanglement cross-linking of high-molecular-weight HA with chemical modification. This cross-linking technique enhances molecular structure cohesion, improves biocompatibility, prolongs degradation time in vivo, and ensures excellent tissue adhesion of the gel.

Usage Details:Refer to the package insert for instructions.


Aowita Biotech has obtained EU ISO 13485 quality management system certification, with products compliant with EU CE certification standards. Production cleanrooms meet GMP/Class 100 standards, and quality control adheres to Class III medical device industry standards.


Rveiling® Vital

Core Benefits

A triple-action skin optimization product delivering deep hydration + collagen activation + texture refinement. Specifically designed for individuals aged 25-45 with early signs of aging who seek skin texture enhancement rather than mere filling. Utilizing dual technologies of natural entanglement and chemical modification, high-molecular-weight hyaluronic acid achieves a finer gel texture and longer-lasting effects. It stands as a highly acclaimed representative of long-lasting corrective products in the medical aesthetics field.


  1. Deep Hydration: Hyaluronic acid molecules form a long-lasting water-retaining network within the dermis.

  2. Immediate Results: Visibly improves dryness and flaking within 72 hours of a single injection.

  3. Long-lasting Hydration: Micro-crosslinked, micro-particle structure sustains hydration for 3-6 months. A full treatment course typically involves 2-3 sessions (spaced 6-12 weeks apart), with effects lasting 12-18 months depending on injection area, technique, and individual metabolism.

  4. Skin Rejuvenation & Repair: Promotes collagen regeneration and stimulates fibroblast activity. Clinical data indicates enhanced production of Type I collagen.

  5. Fine Line Improvement: Visibly reduces superficial dry lines and fine wrinkles around the eyes, forehead, and cheeks.

  6. Texture Restoration: Improves roughness and dullness caused by sun damage and aging, restoring smooth, refined skin texture.

  7. Enhanced Elasticity: Strengthens skin resilience and firmness, improving mild laxity.

  8. Refined Texture: Creates smoother skin feel and more even complexion.

  9. Brightened Radiance: Increases skin translucency for a naturally healthy, youthful glow.

  10. Hydration Lock: Hyaluronic acid molecules bind water molecules, boosting skin moisture content.

  11. Structural Support: Micro-crosslinked mesh structure provides support for lax skin, improving mild depressions and wrinkles.

  12. Cell Activation: Stimulates the skin's own repair mechanisms, promoting the regeneration of collagen and elastic fibers for an inside-out improvement in skin texture.

  13. Treatment Areas: Treatment plans should be tailored to individual differences. A professional physician should select either superficial or deep dermal injection strategies based on skin thickness and muscle activity characteristics.

Key Attributes


Ingredients

Sodium Hyaluronate 20mg/mL, Lidocaine Hydrochloride 3mg/mL, Phosphate Buffered Water for Injection

Gel Consistency

Viscoelastic

Injection Force

10-35N

Indications

Skin plumping,texture improvement

Injection Depth

Superficial or deep dermal layer

Product Specifications

1mL/vial, 2mL/vial

Model

Fine Lines

Recommended Needle

30G blunt needle

Recommended Treatment Protocol

2-3 injections, spaced (6-8) weeks apart for a complete course

Duration of Effect

Results last 12-18 months

Professional Administration

This product should be injected by authorized professionals in regulated medical facilities

Recovery Time

Mild redness and swelling for 1-2 days post-injection; full recovery within 3-7 days

Combined laser treatment


Combined laser treatment

Rveiling® Vital utilizes high molecular weight hyaluronic acid (HA) as its foundation, prepared through unique physical entanglement and precise chemical cross-linking technology to form a three-dimensional network structure of gel particles.

Smooth injection

Soft tissue fit

Shape retention

Natural feel

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

Rveiling® Vital utilizes high molecular weight hyaluronic acid (HA) as its foundation, prepared through unique physical entanglement and precise chemical cross-linking technology to form a three-dimensional network structure of gel particles.

Smooth injection

Soft tissue fit

Shape retention

Natural feel

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

Rveiling® Vital utilizes high molecular weight hyaluronic acid (HA) as its foundation, prepared through unique physical entanglement and precise chemical cross-linking technology to form a three-dimensional network structure of gel particles.

Smooth injection

Soft tissue fit

Shape retention

Natural feel

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

Utilizing dual technologies of natural entanglement and chemical modification of high-molecular-weight hyaluronic acid, a gel system with dense texture and uniform structure is formed. Its core mechanism lies in precisely hydrating the dermis and mimicking the extracellular matrix, effectively improving superficial wrinkles on areas such as the back of the hands, neck, and face caused by dryness and collagen loss. Simultaneously, the gel pursues comprehensive restorative goals: enhancing skin elasticity, refining texture, improving luminosity, and promoting overall rejuvenation. Its immediate filling effect delivers a natural, soft aesthetic result.

Slow degradation

Structural lift

Plump effect

Defined contours

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

Utilizing dual technologies of natural entanglement and chemical modification of high-molecular-weight hyaluronic acid, a gel system with dense texture and uniform structure is formed. Its core mechanism lies in precisely hydrating the dermis and mimicking the extracellular matrix, effectively improving superficial wrinkles on areas such as the back of the hands, neck, and face caused by dryness and collagen loss. Simultaneously, the gel pursues comprehensive restorative goals: enhancing skin elasticity, refining texture, improving luminosity, and promoting overall rejuvenation. Its immediate filling effect delivers a natural, soft aesthetic result.

Slow degradation

Structural lift

Plump effect

Defined contours

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

Utilizing dual technologies of natural entanglement and chemical modification of high-molecular-weight hyaluronic acid, a gel system with dense texture and uniform structure is formed. Its core mechanism lies in precisely hydrating the dermis and mimicking the extracellular matrix, effectively improving superficial wrinkles on areas such as the back of the hands, neck, and face caused by dryness and collagen loss. Simultaneously, the gel pursues comprehensive restorative goals: enhancing skin elasticity, refining texture, improving luminosity, and promoting overall rejuvenation. Its immediate filling effect delivers a natural, soft aesthetic result.

Slow degradation

Structural lift

Plump effect

Defined contours

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

The preparation of Rveiling® Vital Gel begins with the “natural entanglement” of high-purity hyaluronic acid (HA) chains, forming an initial three-dimensional network. This is followed by “chemical modification” for precise anchoring and reinforcement, constructing a stable gel molecular structure that combines flexibility with supportive strength. This process also enables uniform control over the particle size distribution of the gel particles.

Low irritation

Medical-grade

Proven safety

Consistent quality

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

The preparation of Rveiling® Vital Gel begins with the “natural entanglement” of high-purity hyaluronic acid (HA) chains, forming an initial three-dimensional network. This is followed by “chemical modification” for precise anchoring and reinforcement, constructing a stable gel molecular structure that combines flexibility with supportive strength. This process also enables uniform control over the particle size distribution of the gel particles.

Low irritation

Medical-grade

Proven safety

Consistent quality

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

The preparation of Rveiling® Vital Gel begins with the “natural entanglement” of high-purity hyaluronic acid (HA) chains, forming an initial three-dimensional network. This is followed by “chemical modification” for precise anchoring and reinforcement, constructing a stable gel molecular structure that combines flexibility with supportive strength. This process also enables uniform control over the particle size distribution of the gel particles.

Low irritation

Medical-grade

Proven safety

Consistent quality

Cross-linked Hyaluronic Acid Sodium Gel Manufacturer

Show Details

Hide Details

FAQs

1. Why does cross-linked hyaluronic acid last longer than non-cross-linked hyaluronic acid?

Cross-linked hyaluronic acid possesses a stable three-dimensional structure that resists natural enzymatic degradation in the skin. While non-cross-linked hyaluronic acid breaks down within days to a week, cross-linked hyaluronic acid persists in the body for months or longer, delivering extended filling and hydration effects. Our facility employs natural HA entanglement micro-crosslinking technology combined with an efficient BDDE crosslinking process. This ensures excellent biocompatibility and long-lasting efficacy while minimizing inflammation.

2. Is your sodium hyaluronate sourced from animals?

No. Our sodium hyaluronate is produced through microbial fermentation, ensuring it is non-animal-derived and biocompatible. This minimizes allergy risks and guarantees high safety during micro-therapy with implantable fillers.

3. What is the function of lidocaine in the injectable gel?

Lidocaine (0.3%) is used to minimize discomfort during injection, alleviate local pain, and enhance the patient's treatment experience. Each batch of our product undergoes rigorous quality control to ensure lidocaine concentration and safety in clinical use.

4. How does your cross-linking process preserve hyaluronic acid's natural structure?

Our cross-linking process employs low-level BDDE cross-linking and chemical modification to stabilize hyaluronic acid molecules while maintaining their natural biological structure. This balanced outcome delivers exceptional elasticity, biocompatibility, and hydration retention in treating superficial dry lines, fine wrinkles, and anti-aging concerns on areas like the hands, neck, forehead, and cheeks.

5. How do clinics or suppliers collaborate with your factory for OEM or bulk supply?

As a specialized manufacturer and global supplier, we partner with medical clinics and brand distributors for OEM, private labeling, or bulk supply. We provide comprehensive technical documentation, quality certifications, and global logistics support to ensure safe, efficient delivery.

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