Rveiling® Calcium Hydroxyphosphate Injectable Facial Filler
Product Overview
Rveiling® HA-CaHA Injectable Facial Filler is a milky white, sterile, biodegradable viscous gel implant. Utilizing a pre-filled syringe system, it combines instant filling with long-lasting effects to restore skin tissue volume through injection, achieving facial rejuvenation and aesthetic contouring.
Specifications
1 mL/vial, 2 mL/vial, 3 mL/vial
Active Ingredients
Sodium Hyaluronate, Calcium Hydroxyapatite Microspheres, Lidocaine Hydrochloride, Sodium Chloride, Injection Water, Phosphate Buffer System.
Structure and Composition
Rveiling® HA-CaHA Injectable Facial Filler is a milky white viscous gel, sterile, latex-free, pyrogen-free, semi-solid, biodegradable dermal implant. Primarily composed of synthetic calcium hydroxyapatite microspheres (30.7% concentration) suspended within a cross-linked sodium hyaluronate gel carrier. The gel carrier consists mainly of cross-linked sodium hyaluronate, lidocaine hydrochloride, sodium chloride, phosphate buffer system, and water for injection. The sodium hyaluronate is produced via microbial fermentation, with a labeled concentration of 20mg/ml sodium hyaluronate and 0.3% lidocaine hydrochloride. It is packaged in a single-use, pre-filled syringe. The addition of lidocaine hydrochloride reduces pain during treatment, enhancing patient comfort.
Product Component
Lidocaine is a hybrid dermal filler that uses cross-linked hyaluronic acid (20 mg/mL) combined with calcium hydroxyphosphate (30.7% w/w) microspheres and lidocaine (0.3%) to form a single filler, unlike artificial bone meal microsphere products, which are pre-mixed and do not need to be paired with additional hyaluronic acid or other gels prior to injection. It is a sterile, viscous, latex-free, non-thermal, semi-solid, biodegradable dermal implant.
Product Performance
Rveiling® HA-CaHA Injectable Facial Filler primarily consists of cross-linked sodium hyaluronate gel particles and CaHA microspheres. The median particle size of CaHA microspheres is 32μm ± 6μm, with at least 95% of microspheres measuring between 25–50μm. This product serves as a dermal filler, injected into the deep dermis, deep subcutaneous tissue, and superficial periosteum to enhance skin volume. It delivers immediate results at the injection site, while the CaHA microspheres prolong the filling effect.
Mechanism of Action
Rveiling® Calcium Hydroxyapatite (CaHA) Injectable Facial Filler achieves soft tissue augmentation and rejuvenation through a synergistic mechanism. Its action begins with a composite system: the gel carrier provides immediate volume and subsequently biodegrades, while the retained CaHA microspheres form a biological scaffold that activates the body's beneficial repair response. This process precisely recruits key reparative cells such as macrophages and fibroblasts, forming a “regenerative microenvironment” around the microspheres. Through sustained biochemical and mechanical signaling, it powerfully activates the synthetic function of fibroblasts, efficiently secreting Type I and Type III collagen to form a novel autologous collagen network. Ultimately, CaHA microspheres degrade slowly after guiding collagen regeneration, achieving a seamless transition from “physical filling” to “biological regeneration” in therapeutic action. This delivers natural, long-lasting rejuvenation effects.
Indications
Suitable for correcting deep facial skin depressions, cheek augmentation, wrinkles, marionette lines, and jawline contouring; repairing/ correcting facial fat loss (atrophy) in AIDS patients. HA-CaHA facial filler gel can be diluted in varying ratios for wrinkle repair on the face, neck, arms, abdomen, buttocks, and other areas.
Sterilization Method: The gel inside the pre-filled syringe is sterilized by high-temperature steam; the injection needle is sterilized by ethylene oxide. Usage Specifications: This product is for single-use only. Shelf Life: 36 months. Precautions: Strict adherence to sterile surgical procedures is mandatory during use. Refer to the package insert for detailed instructions. Precautions: Strict adherence to sterile surgical procedures is mandatory during use. Refer to the package insert for detailed instructions.
Principle of Operation
1. Biodegradable Gel Carrier
The gel component is gradually degraded and absorbed by the body, allowing soft tissue regeneration to take its place over time.
2. Stable Calcium Hydroxyapatite Microspheres
The calcium hydroxyapatite microspheres remain at the injection site, providing a scaffold for collagen growth and long-lasting structural support.
3. Lidocaine for Local Anesthesia
The formula contains lidocaine, which offers short-term local anesthesia, ensuring a comfortable injection experience for patients.
4. Long-Lasting but Non-Permanent Results
The calcium hydroxyapatite microspheres deliver durable facial contour enhancement and volume restoration, while maintaining biocompatibility and gradual absorption over time.
Products Status
Mechanism of action
Rveiling® HA-CaHA Composite Filler: Dual-action in one syringe. Deeply builds firm structural support to lift facial contours; finely sculpts superficial layers to create natural shaping power for plump, dimensional skin. Simultaneously stimulates collagen regeneration for long-lasting firmness and skin texture improvement.
Reveiling® HA-CaHA facial filler, when implanted into soft tissue, undergoes gradual degradation where the gel matrix breaks down before the CaHA microspheres. These microspheres provide long-term structural support while stimulating natural collagen regeneration.
Revealing® HA-CaHA Implant Tissue: Pre- and Post-Treatment Effect Comparison Long-lasting activation of collagen regeneration Stabilizes facial tissue volume Reshapes smooth contour lines Achieves a natural, youthful facial appearance.
Back of the hand
Key attributes
Transport conditions | transported at normal temperature, the transport cycle should not exceed1 month |
|---|---|
Storage condition | 2-25°C,prohibit freezing, avoid sunlight |
Specification | 1 mL/vial 2 mL/vial 3 mL/vial |
Transport Pakeage | 50-100 pieces per box |
HA Gel Carriers | 69.0% |
CaHA Microsphere | 30.7% |
Lidocaine | 0.3% |
Injection Areas |
It should be used by an authorized practitioner. Do not re-sterilize or mix with other products. |
Injection Depth | Subcutaneous tissue, from the middle to deep layers; periosteum, upper layer |
Duration | 12-24 Months |
Before treatment：
Tell your physician about all medications you are taking and your past treatment history.
Foods that increase the chance of bleeding and cause bruising should be avoided for the time being, such as: ginkgo, fish oil, aspirin drugs, vitamin E, etc.
Consult your physician if you are allergic to the drug, breastfeeding, or during pregnancy.
After treatment ：
Avoid alcohol and strenuous exercise for twenty-four hours.
Apply light make-up after twenty-four hours and avoid the location of the pinholes.
Intrusive treatments, facial massages, and facial aesthetic procedures are not recommended for two weeks.
Avoid prolonged sun exposure, exposure to UV light, cold temperatures, and hot treatments.
Temporary redness, swelling, soreness and bruising are natural and will subside in five to seven days.
FAQs
1. Injectable Hydroxyapatite Microsphere Facial Filler
Our calcium hydroxyapatite injectable facial filler is formulated with biocompatible calcium hydroxyapatite microspheres suspended in a biodegradable gel particle carrier. Following implantation, the gel particles gradually degrade and metabolize, while the microspheres provide long-term structural support and stimulate natural collagen regeneration.
2. Can we customize packaging for OEM or private label production?
Yes. As a professional B2B manufacturer and supplier, we offer OEM and ODM customization services, including logo and packaging design. We support clinics, distributors, and medical aesthetic brands with flexible collaboration models.
3. What are the primary applications of injectable calcium hydroxylapatite facial fillers?
This injectable implant filler is suitable for correcting moderate to severe facial wrinkles, contouring, wrinkle reduction, skin folds, and restoring volume loss in the hands. Injected into the deep dermis or upper soft tissue above the periosteum, it delivers non-permanent yet long-lasting enhancement effects.
4. How long do the effects of hydroxyapatite microsphere facial fillers last?
Typically, results persist for 24 to 36 months or longer, depending on the injection site, technique, and patient metabolism. The calcium hydroxyapatite microspheres continue stimulating collagen growth, delivering sustained volume and firmness over time.
5. What certifications and quality standards do you provide for B2B partners?
Our manufacturing strictly adheres to ISO 13485, GMP, and CE certification—globally recognized standards for medical device production quality and safety. Each production batch undergoes exhaustive biological performance testing covering biocompatibility, sterility, pyrogen-free status, and functional integrity. This rigorous process ensures 100% batch compliance, delivering consistent reliability you can trust.
