Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder Professional B2B Supplier for Injectable & Regenerative Applications

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications
Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

PLLA-PEG Microspheres Freeze-Dried Powder- Professional B2B Supplier for lnjectable & Regenerative Applications

Type

Cheeks

Type

Cheeks

Type

Cheeks

Application

Applications: Suitable for individuals aged 18 and above, this product improves and replenishes structural depressions such as facial wrinkles, temples, forehead, and cheeks, softening facial contours and stimulating fibroblast proliferation and collagen production.

Application

Applications: Suitable for individuals aged 18 and above, this product improves and replenishes structural depressions such as facial wrinkles, temples, forehead, and cheeks, softening facial contours and stimulating fibroblast proliferation and collagen production.

Application

Applications: Suitable for individuals aged 18 and above, this product improves and replenishes structural depressions such as facial wrinkles, temples, forehead, and cheeks, softening facial contours and stimulating fibroblast proliferation and collagen production.

Place of Origin

China

Place of Origin

China

Place of Origin

China

Brand Name

Rveiling

Brand Name

Rveiling

Brand Name

Rveiling

Sterile PLLA-PEG microsphere formula for facial contouring, anti-aging, and collagen-stimulating aesthetic treatments.

Sterile PLLA-PEG microsphere formula for facial contouring, anti-aging, and collagen-stimulating aesthetic treatments.

Sterile PLLA-PEG microsphere formula for facial contouring, anti-aging, and collagen-stimulating aesthetic treatments.

Product Notes


  • Aseptic Procedure:
    Injection therapy carries an infection risk. Ensure strict aseptic conditions and local disinfection before use.


  • Injection Risks:
    Patients may develop small nodules or swelling due to injection technique or dosage. Avoid overcorrection.


  • Treatment Effectiveness:
    Results and duration vary depending on defect type, injection depth, and individual body composition.


  • Post-Treatment Care:
    Avoid strong heat, extreme cold, alcohol, or spicy food for 7 days. Refrain from massages or skincare on the treated area without professional advice.


Product Description

Freeze-Dried Powder is a premium injectable formulation composed of Poly(L-lactic acid)-Polyethylene glycol (PLLA-PEG) microspheres, mannitol, and sodium hyaluronate gel. This advanced combination stimulates natural collagen regeneration, restoring facial volume and improving skin elasticity for long-lasting rejuvenation.

Key attributes


Storage condition

2-10°C refrigerated, used up within 24 hours after opening the bottle

Transport conditions

Transport at room temperature (not exceeding 30°C) should not exceed 1 month, otherwise cold chain transport

Contraindications

  • Avoid use in patients with autoimmune diseases (active or early phase) or those receiving immunosuppressive therapy.

  • Do not use on areas with active skin infections or in patients with herpes.

  • Contraindicated for individuals allergic to hyaluronic acid, poly(L-lactic acid), lactic acid, mannitol, polyethylene glycol, or lidocaine.

  • Not suitable for patients with bleeding disorders or those using anticoagulants, thrombolytics, or platelet inhibitors within the past two weeks.

  • Pregnant, breastfeeding, and underage patients are prohibited from use.

  • Avoid in patients prone to keloids or hypertrophic scars.


Supports Long-Term Collagen Regeneration for Natural Tissue Restoration and Firmness

Sustained biostimulation

Gradual volumizing effect

Improved skin elasticity

Structural support renewal

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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Supports Long-Term Collagen Regeneration for Natural Tissue Restoration and Firmness

Sustained biostimulation

Gradual volumizing effect

Improved skin elasticity

Structural support renewal

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

Show Details

Hide Details

Supports Long-Term Collagen Regeneration for Natural Tissue Restoration and Firmness

Sustained biostimulation

Gradual volumizing effect

Improved skin elasticity

Structural support renewal

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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High-Uniformity Microsphere Size Ensures Stable Performance and Smooth Injection Handling

Controlled particle dispersion

Reduced clogging risk

Consistent flow behavior

Predictable treatment outcome

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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High-Uniformity Microsphere Size Ensures Stable Performance and Smooth Injection Handling

Controlled particle dispersion

Reduced clogging risk

Consistent flow behavior

Predictable treatment outcome

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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High-Uniformity Microsphere Size Ensures Stable Performance and Smooth Injection Handling

Controlled particle dispersion

Reduced clogging risk

Consistent flow behavior

Predictable treatment outcome

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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Freeze-Dried PEG Composite Enhances Storage Stability and Easy Reconstitution for Clinical Use

Extended shelf life

Convenient mixing process

Maintains product activity

Reliable clinical handling

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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Freeze-Dried PEG Composite Enhances Storage Stability and Easy Reconstitution for Clinical Use

Extended shelf life

Convenient mixing process

Maintains product activity

Reliable clinical handling

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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Freeze-Dried PEG Composite Enhances Storage Stability and Easy Reconstitution for Clinical Use

Extended shelf life

Convenient mixing process

Maintains product activity

Reliable clinical handling

Poly(L-lactic acid)-PEG Microspheres Freeze-Dried Powder – Professional B2B Supplier for Injectable & Regenerative Applications

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FAQs

1. What are the core competitive advantages of your PLLA/PEG microsphere freeze-dried powder compared to traditional HA or CaHA fillers?

Our PLLA/PEG microsphere freeze-dried powder has essential differences and unique advantages compared to traditional hyaluronic acid (HA) or calcium hydroxyapatite (CaHA) fillers:

  1. Mechanism Difference: Traditional fillers rely primarily on physical filling to achieve immediate volume gain. Our PLLA product is a biostimulator that stimulates the production of new autologous collagen in the patient's dermis and subcutaneous tissue , achieving a more natural and gradual volume restoration.

  2. Long-lasting and natural-looking: PLLA-induced collagen regeneration is long-lasting, typically lasting two years or longer . The results develop gradually over time, resulting in a more natural and realistic appearance that is less likely to appear overfilled or artificial.

  3. Tissue Improvement: PLLA is more than just “filling”; it’s a fundamental improvement to skin quality , including skin thickness, elasticity, and firmness.

2. Are the effects of PLLA/PEG freeze-dried powder injections immediately visible? How should B2B partners manage expectations and explain the gradual effects to their clients?

The effects of PLLA products are not immediately visible. This is a characteristic of its mechanism of action and a key point that B2B partners need to clearly communicate to their customers:

  1. Initial injection: After injection, the water in the solution (reconstitution) causes a temporary increase in volume . After about 1-2 days, the water is absorbed and the volume temporarily decreases.

  2. Gradual effect: The real collagen regeneration effect will be seen after treatment.$4$Weeks of treatment begin to show signs of improvement and the symptoms will be less severe after the full course of treatment (usually$3$to$4$After several months, it reaches its best condition .

  3. Expectation Management: We recommend that organizations emphasize the "lasting, natural, and gradual" improvements in volume and quality that products bring, rather than "instantaneous changes." Clear expectation management is key to improving customer satisfaction and loyalty.

3. Does your company's PLLA/PEG lyophilized powder have specific restrictions or recommendations for injection areas? How can it be safely applied to complex areas (such as the periorbital area and lips)?

Our PLLA/PEG lyophilized powder products are mainly used to treat volume loss and wrinkles in deep and subcutaneous tissues :

  1. Recommended areas: Suitable for areas with volume loss due to collagen loss, such as cheek hollows, temples, nasolabial folds, marionette lines, and mandibular contours .

  2. Restricted areas: According to the product instructions, PLLA products are not recommended for use in deep and ultra-deep tissues, the lip vermilion area , or areas where extremely precise local volume restoration is required (such as the superficial periorbital area).

  3. Safety considerations: For complex areas, we require our partner institutions to use blunt-tip needles , strictly control the injection plane (deep layer), and avoid nerves and blood vessels to ensure uniform diffusion and safe absorption of the product .

4. How does your company's PLLA/PEG microsphere lyophilized powder packaging design and sterilization process ensure product sterility and microsphere quality?

Our product quality control and sterility assurance meet strict medical device standards:

  1. Microsphere quality: The particle size and morphology of PLLA microspheres are strictly controlled to ensure their uniform dispersion after reconstitution and stable degradation rate in the body , which is the key to ensuring the collagen stimulation effect.

  2. Sterilization process: The freeze-dried powder is sterilized by ethylene oxide , which is an efficient sterilization method suitable for heat-sensitive medical devices, ensuring the absolute sterility of the product before opening .

  3. Packaging stability: The lyophilized powder is packaged in sealed ampoules , which maximizes the shelf life of the product while ensuring the convenience of transportation and storage (store at room temperature away from light).

5. Regarding the long-term maintenance of PLLA products, what follow-up and combined treatment recommendations do you offer B2B partners?

The value of PLLA products lies in their long-term effectiveness. We provide professional follow-up and combined treatment guidance:

  1. Long-term follow - up: It is recommended that cooperative institutions establish long-term customer files and$6$to$12$Regular follow-up is conducted every three months to evaluate the maintenance of collagen and discuss with the client whether a consolidation (Touch-up) injection is needed .

  2. Combination Therapy Recommendations: PLLA can serve as a foundation for underlying volume restoration , combined with upper-layer botulinum toxin (for dynamic wrinkles) or epidermal phototherapy (for skin texture improvement) to optimize overall rejuvenation . We offer professional training on combined treatment options.

  3. Client education: Focus on educating clients that post-operative massage is a key component of treatment effectiveness and must be performed consistently to ensure even distribution of microspheres and maximize collagen regeneration effects.

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