Cross-Linked Sodium Hyaluronate Gel for Injection Manufacturer

Cross-Linked Sodium Hyaluronate Gel for Injection Manufacturer

 Best HA Cross-linked Factory for Cheeks | Aowita

Cheeks

Rveiling®

 Best HA Cross-linked Factory for Cheeks | Aowita

Cheeks

Rveiling®

 Best HA Cross-linked Factory for Cheeks | Aowita

Cheeks

Rveiling®

Rveiling® Cross-linked Sodium Hyaluronate Gel for Injection

Type

Cheeks

Type

Cheeks

Type

Cheeks

Application

Suitable for individuals aged 18 and above who require increased facial tissue volume, including deep facial contouring, mid-layer filling, and deep dermal injections to improve skin appearance.

Application

Suitable for individuals aged 18 and above who require increased facial tissue volume, including deep facial contouring, mid-layer filling, and deep dermal injections to improve skin appearance.

Application

Suitable for individuals aged 18 and above who require increased facial tissue volume, including deep facial contouring, mid-layer filling, and deep dermal injections to improve skin appearance.

Place of Origin

China

Place of Origin

China

Place of Origin

China

Brand Name

Rveiling

Brand Name

Rveiling

Brand Name

Rveiling

Product Overview: Rveiling® Cross-Linked Sodium Hyaluronate Facial Filler

1. Product Positioning & Intended Use

Professional Injectable Dermal Filler Raw Material

Rveiling® Cross-Linked Sodium Hyaluronate Gel for Injection is a medical-grade injectable gel designed for professional aesthetic applications. As a manufacturer-oriented solution, it is developed to support dermal filler production, OEM/ODM cooperation, and clinical aesthetic use under regulated medical environments.

The product is supplied in sterile, pre-filled syringes and formulated to meet the performance, safety, and consistency requirements expected by global aesthetic medicine brands and professional distributors.

2. Available Models and Specifications

Syringe Volume and Injection Depth Options

Cross-Linked Sodium Hyaluronate Gel for Injection is available in standardized syringe formats to accommodate different clinical protocols and product development needs:

  • 1 mL / syringe

  • 2 mL / syringe

Injection depth models include:

  • Derm: suitable for mid-dermal correction

  • Deep: designed for mid-to-deep dermal tissue applications

Product Composition and Structural Characteristics

1. Ingredient Profile

Precisely Balanced Injectable Formulation

The formulation is composed of the following pharmaceutical-grade components:

  • Sodium hyaluronate

  • Lidocaine hydrochloride

  • BDDE cross-linking agent

  • Sodium chloride

  • Phosphate buffer system

  • Water for injection

Each ingredient is selected to ensure stability, injectability, and biocompatibility while supporting consistent gel performance.

2. Structural Composition

Cross-Linked Gel Particle Suspension

The product consists of a suspension of cross-linked sodium hyaluronate gel particles combined with a controlled proportion of free sodium hyaluronate. The hyaluronic acid is produced via microbial fermentation, ensuring high purity and reproducibility.

The gel is packaged in a single-use, pre-filled syringe to minimize contamination risk and ensure precise dosing. Lidocaine hydrochloride is incorporated to reduce injection discomfort and improve patient experience during treatment.

Mechanism of Action and Clinical Performance

1. Mechanism of Action

Dermal Tissue Filling and Volume Restoration

Cross-Linked Sodium Hyaluronate Filler functions as a dermal tissue filler. Upon injection into targeted dermal layers, the gel provides mechanical support, restores volume, and enhances contour definition.

The cross-linked HA matrix maintains structural integrity within the tissue, contributing to sustained aesthetic outcomes.

2. Indications for Use

Mid-to-Deep Dermal Correction Applications

This product is indicated for injection into the mid-to-deep layers of facial dermal tissue in adults aged 18 years and above. Typical application areas include:

  • Mid-face wrinkles

  • Deep dermal depressions

  • Chin contouring

  • Cheek volumization

  • Jawline definition

The treatment aims to improve facial appearance by correcting shape and restoring youthful contours.

EYE-CATCHING RESULTS


Visual representation of cross-linked hyaluronic acid gel texture and elasticityThree-dimensional polymer network formed through controlled cross-linking process

Cross-linked Sodium Hyaluronate Gel Granules for Injection

Rveiling® Molecular sieve technology Different particle size products


Rveiling® promotes collagen renewal and remodelling of the dermal structure

Key attributes


Ingredients

Sodium Hyaluronate, Lidocaine Hydrochloride, BDDE crosslinking agent, Sodium Chloride, Injection Water Phosphate Buffer System

Product Specifications

1mL/syringe, 2mL/syringe

Model

Derm/Deep

Injection Force

10-40N

Gel Consistency

Viscoelastic

Indications

Correction of skin depressions, facial contouring

Injection Depth

Mid to deep dermis

Injection Areas

For treating facial wrinkles and deep skin depressions, including the chin, cheeks, jawline, and temples.

Recommended Needle

27G sharp needle/25G blunt cannula needle

Recommended Treatment Protocol

Treatment plans should be individualized. A qualified practitioner should select injection strategies targeting the mid-dermis or deep dermis based on skin thickness and muscle activity characteristics.

Duration of Effect

Results typically last 12-18 months. Effectiveness and duration depend on defect type, injection depth, and individual physiology.

Professional Administration

This product must be administered by authorized professionals in regulated medical facilities.

Recovery Time

Mild redness and swelling may persist for 1-2 days post-injection, with full recovery typically occurring within 3-7 days.

Optimized HA cross-linking structure forms a tightly intertwined molecular network with excellent biocompatibility, delivering a soft, skin-friendly gel texture and superior subcutaneous adhesion. No displacement ensures long-lasting, natural-looking filling results.

Smooth injection flow

Elastic tissue integration

Natural contour shaping

Comfortable patient feel

HA Entanglement Crosslinking Technology Gel aowitahyaluronic acid manufacturers in china

Optimized HA cross-linking structure forms a tightly intertwined molecular network with excellent biocompatibility, delivering a soft, skin-friendly gel texture and superior subcutaneous adhesion. No displacement ensures long-lasting, natural-looking filling results.

Smooth injection flow

Elastic tissue integration

Natural contour shaping

Comfortable patient feel

HA Entanglement Crosslinking Technology Gel aowitahyaluronic acid manufacturers in china

Optimized HA cross-linking structure forms a tightly intertwined molecular network with excellent biocompatibility, delivering a soft, skin-friendly gel texture and superior subcutaneous adhesion. No displacement ensures long-lasting, natural-looking filling results.

Smooth injection flow

Elastic tissue integration

Natural contour shaping

Comfortable patient feel

HA Entanglement Crosslinking Technology Gel aowitahyaluronic acid manufacturers in china

High molecular weight HA utilizes natural entanglement cross-linking technology with chemical modification and enhanced cross-linking density to construct flexible, skin-friendly hyaluronic acid gel particles. These particles deliver exceptional viscoelastic properties, ensuring smooth injection and natural filling effects while enhancing product stability for long-lasting aesthetic results.

Slow biodegradation rate

Maintains structural definition

Enhances skin suppleness

Consistent performance outcomes

Professional injectable gel with controlled rheology for aesthetic material development

High molecular weight HA utilizes natural entanglement cross-linking technology with chemical modification and enhanced cross-linking density to construct flexible, skin-friendly hyaluronic acid gel particles. These particles deliver exceptional viscoelastic properties, ensuring smooth injection and natural filling effects while enhancing product stability for long-lasting aesthetic results.

Slow biodegradation rate

Maintains structural definition

Enhances skin suppleness

Consistent performance outcomes

Professional injectable gel with controlled rheology for aesthetic material development

High molecular weight HA utilizes natural entanglement cross-linking technology with chemical modification and enhanced cross-linking density to construct flexible, skin-friendly hyaluronic acid gel particles. These particles deliver exceptional viscoelastic properties, ensuring smooth injection and natural filling effects while enhancing product stability for long-lasting aesthetic results.

Slow biodegradation rate

Maintains structural definition

Enhances skin suppleness

Consistent performance outcomes

Professional injectable gel with controlled rheology for aesthetic material development

Rveiling® Cross-linked Hyaluronic Acid (HA) Gel, Flexible and Skin-Friendly Gel Particles, Promotes Collagen Renewal and Dermal Structure Remodeling

Low inflammatory response

Biocompatible cross-linking

Reliable batch consistency

Third-party quality testing

Aowita  Hyaluronic Acid Manufacturer promotes collagen renewal and remodelling of the dermal structure

Rveiling® Cross-linked Hyaluronic Acid (HA) Gel, Flexible and Skin-Friendly Gel Particles, Promotes Collagen Renewal and Dermal Structure Remodeling

Low inflammatory response

Biocompatible cross-linking

Reliable batch consistency

Third-party quality testing

Aowita  Hyaluronic Acid Manufacturer promotes collagen renewal and remodelling of the dermal structure

Rveiling® Cross-linked Hyaluronic Acid (HA) Gel, Flexible and Skin-Friendly Gel Particles, Promotes Collagen Renewal and Dermal Structure Remodeling

Low inflammatory response

Biocompatible cross-linking

Reliable batch consistency

Third-party quality testing

Aowita  Hyaluronic Acid Manufacturer promotes collagen renewal and remodelling of the dermal structure

FAQs

1. Why does cross-linked hyaluronic acid last longer than non-crosslinked HA?

Cross-linked hyaluronic acid possesses a stable three-dimensional structure that resists natural enzymatic degradation within the skin. While non-cross-linked hyaluronic acid breaks down within days to a week, cross-linked hyaluronic acid persists in the body for months or even longer, delivering extended filling and hydration effects. Rveiling® employs natural HA entanglement cross-linking technology combined with an efficient BDDE-modified cross-linking process, ensuring excellent biocompatibility and long-lasting efficacy in product applications.

2. Is your cross-linked hyaluronic acid derived from animals?

No. Our sodium hyaluronate raw material is produced through microbial fermentation, utilizing non-animal-derived ingredients. This reduces the risk of allergic reactions and ensures the implantable filler maintains a high level of safety throughout the treatment process.

3. What is the purpose of lidocaine in the injectable gel?

Lidocaine (0.3%) is used to reduce discomfort during injection, alleviate local pain, and enhance the patient's treatment experience. Each batch of our product undergoes rigorous quality control to ensure the safety of lidocaine concentration in clinical use.

4. How does your cross-linking process preserve the natural structure of hyaluronic acid?

Our cross-linking process employs a dual approach: natural entanglement cross-linking technology for high molecular weight HA combined with low-level BDDE chemical modification cross-linking. This stabilizes the molecular structure of sodium hyaluronate while preserving its natural biological architecture. This balanced outcome delivers exceptional viscoelasticity, biocompatibility, and water retention properties during therapeutic enhancement.

5. How can clinics or distributors work with your factory for OEM or bulk supply?

We are a specialized manufacturer and global supplier dedicated to partnering with medical clinics, brands, and distributors for OEM, private label, or bulk supply. We provide comprehensive technical documentation, quality certifications, and global logistics support to ensure safe and efficient delivery.

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